Feb 19, 2013 PXE News

February 19, 2013
Stem Cell Therapy Experiments in the PXE Mouse
Pseudoxanthoma elasticum (PXE) has been confirmed as a metabolic disorder caused by a protein that malfunctions in the liver. Stem cells derived from bone marrow are of particular interest to PXE researchers because previous studies have shown their capacity to develop into liver cells and be successfully used in patients with liver disorders. A study conducted by researchers in Dr. Jouni Uitto’s laboratory at Jefferson Medical College explored the effects of several techniques for introducing stem cells into PXE knockout mice.

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