News

November 3, 2009
Do Other Genes Influence the Severity of PXE?

August 6, 2009
Update on Treatments for Retinal Bleeding Caused by Pseudoxanthoma Elasticum
The retinal bleeding caused by pseudoxanthoma elasticum (PXE) is the result of choroidal neovascularization (CNV) which can leak blood and cause scarring in the eye, leading to vision loss.  Two anti-VEGF drugs, Lucentis and Avastin, have shown the most improvement in the majority of individuals treated for CNV.

February 6, 2009
Dietary Magnesium Prevented Tissue Mineralization in the PXE Mouse
Read about the effects of altered magnesium or phosphate diets on the tissue mineralization in the PXE mouse.

December 22, 2008
A Possible Drug Alternative to Avastin® and Lucentis®
Recently a Japanese company named OPKO created a new drug, called Bevasiranib, which, like Avastin® and Lucentis®, works to prevent VEGF proteins from causing leaky blood vessels to grow. How is it different from Avastin and Lucentis?

October 11, 2008
5th Annual North American ABC Meeting
A key session at the ABC meeting, titled "Pseudoxanthoma elasticum, ABCC6, and Vitamin K?", generated vigorous discussion, and PXE International is pursuing new leads. 

September 15, 2008
Clear Evidence: PXE Is a Metabolic Disease
Here is scientific evidence supporting the theory that pseudoxanthoma elasticum (PXE) is a metabolic disease, based on results from a recent study in the PXE mouse.

September 15, 2008
Clinical Trials Comparing Avastin® and Lucentis®
The trial is studying how safe and effective Avastin® is compared to Lucentis® for people who have retinal bleeding due to Age-Related Macular Degeneration (AMD).  It is also studying two different dosing schedules for Avastin and Lucentis.

July 9, 2008
Human Gene Therapy for Treating Blinding Eye Disease
Read about recent developments in human gene therapy for treating Leber´s Congenital Amaurosis (LCA), a blinding eye disease.

June 9, 2008
Vitamin K Precursor Might Be Involved in Pseudoxanthoma Elasticum
Does the absence of ABCC6 in PXEers prevent the liver from providing sufficient vitamin K to the periphery?

November 1, 2007
PXE International Develops Genetic Test for PXE
After almost eight years of work, PXE International brings you the genetic test for PXE!  Partnering with GeneDx, a laboratory in Gaithersburg, MD, we are delighted that we are able to finally offer this test.